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AFM / OT and Advanced Optics
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Nanoscience
Electrical and Magnetic
Cell Mechanics and Adhesion
Single Molecule Force Spectroscopy
Nanomanipulation and Lithography
Raman, TERS and SNOM
Atomic Force MicroscopyAutomated Force SpectroscopyOptical TweezersCellular Adhesion / Cytomechanics
Atomic Force Microscopy
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VIDEO - Streptavidin binding to biotinylated DNA origami at 50 frames and 5000 lines/sec
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VIDEO - High-speed imaging of DNA origami at 35 frames/sec
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VIDEO - High-speed imaging of DNA at 50 frames/sec
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Kelvin Probe Microscopy (KPM) on reference sample
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Force mapping on elastomer
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Contact Resonance frequency image of glas
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DNA imaged with PeakForce Tapping mode
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Piezoresponse Force Microscopy of a ferroelectric copolymer
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Living A549 cells - Correlative AFM and STED
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Living Vero cells
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DNA Origami at 150 lines/sec
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Correlative STED and AFM images of nanorulers
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Correlative STED and AFM images of isolated sacculi of Bacillus subtilis
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VIDEO - Real-time rapture of microtubules - Correlative AFM and STED measurements
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VIDEO - Real-time bending of microtubules - Correlative AFM and STED measurements
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VIDEO - Stimulation of living fibroblast cells - Correlative AFM and STED measurements
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Nanoruler - AFM and STED
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Living A549 cells - Simultaneous AFM and STED
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Astrocytes
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Imaging of bacteria S-layer with QI™
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Simultaneous AFM and FLIM measurements
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TERS mapping
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Enhancement of fluorescence with gold nanoparticles
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J-aggregates
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Paracoccus Seriniphilus bacteria
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Living CHO on gold electrode
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Simultaneous AFM and STED of Living fibroblasts - Actin Filament Imaging
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Simultaneous AFM and STED of Living fibroblasts
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Cell/particle interaction - AFM with confocal microscopy
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MIPAM particle
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High-resolution imaging on sperm
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Cow tooth – etched - AFM with upright microscopy
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JPK logo - piezo-response microscopy
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Living CHO cell
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Rad51 proteins bound to DNA - AFM with fluorescence microscopy
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Fibronectin unfolding
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DNA on octadecylamine
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Pentacene layers
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DNA at -25 °C
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Melting of a thin film of polystyrene
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CHO cell - AFM with phase contrast
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Striped gold layer surface
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QI™ DNA - Major and minor grooves
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Recognition microscopy on biotin bead
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Recognition on living keratinocyte cells
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QI™-CAFM on battery electrode
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DNA origami - faceman
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QI™-EFM on NIPAM particles
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Twisted insulin fibrils
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QI™-KPM on an interdigitated electrode
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Living CHO cells - AFM with fluorescence microscopy
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Tendon tissue
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Herpes Simplex Viruses
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Stretching of plastic Parafilm slide
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Bacteriorhodopsin membrane - QI™ mode
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Block-Co-Polymer thin section
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Cell division E-coli bacteria
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Microrheology on silica beads
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Stretching of plastic film
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Human dental enamel
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Scanning thermal microscopy
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PHB/V spherulite crystallization.
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PFM lithograthy
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CAFM on CU conduct layer
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MFM on NiFe square structure
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KPM on SRAM
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Dendronized polymer
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Calcid - True atomic lattice resolution
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Kraton
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Hexacontane
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Crystalline polyethylene at -120°C
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VIDEO - Live CHO cell dynamics
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Tomato Bushy Stunt Virus
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Electrostatic Force Microscopy (EFM) on SRAM
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Bacteria on pyrite surface - AFM with upright fluorescence microscopy
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Mouse cerebellum tissue - AFM with upright fluorescence microscopy
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Plasmid DNA imaged in HyperDrive™ mode in buffer
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Conductive QI™ measurement of a graphene flake
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KPG7 cell dynamics
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Living Candida albicans - AFM with phase contrast
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HeLa cell in buffer - AFM with STORM
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Living KPG7 cell at 37°C - AFM and phase contrast
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Melting of lipid domains in buffer
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Collagen in liquid, 70Hz line rate
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Lambda phage DNA in liquid
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Atomic resolution of mica taken on an optical microscope
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Bacteriorhodopsin in buffer
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Artificial polyprotein made of non-mechanical protein GB1
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PTFE (Teflon™) layer
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MFM on hard drive
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Kelvin Probe Microscopy (KPM) on an interdigitated electrode
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Optically active conductive polymer film
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STM of arachidic acid molecules
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Electrical oxidation on silicon substrate
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Living fibroblast cell - AFM with phase contrast
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Desulfobulbus bacterial cells
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MFM images of rectangular magnetic structures
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MFM images of a double T magnetic structure
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MFM images of six rectangular magnetic structures
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MFM images of a square magnetic structure
NanoWizard® NanoScience AFM
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MIPAM particle
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JPK logo - piezo-response microscopy
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DNA on octadecylamine
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Pentacene layers
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Melting of a thin film of polystyrene
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Striped gold layer surface
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QI™-CAFM on battery electrode
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QI™-EFM on NIPAM particles
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QI™-KPM on an interdigitated electrode
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Stretching of plastic Parafilm slide
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Block-Co-Polymer thin section
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Microrheology on silica beads
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Stretching of plastic film
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Scanning thermal microscopy
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PHB/V spherulite crystallization.
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PFM lithograthy
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CAFM on CU conduct layer
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MFM on NiFe square structure
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KPM on SRAM
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Dendronized polymer
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Calcid - True atomic lattice resolution
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Kraton
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Hexacontane
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Crystalline polyethylene at -120°C
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Electrostatic Force Microscopy (EFM) on SRAM
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Conductive QI™ measurement of a graphene flake
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Living KPG7 cell at 37°C - AFM and phase contrast
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Atomic resolution of mica taken on an optical microscope
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Artificial polyprotein made of non-mechanical protein GB1
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PTFE (Teflon™) layer
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MFM on hard drive
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Kelvin Probe Microscopy (KPM) on an interdigitated electrode
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Optically active conductive polymer film
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STM of arachidic acid molecules
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Electrical oxidation on silicon substrate
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MFM images of rectangular magnetic structures
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MFM images of a double T magnetic structure
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MFM images of six rectangular magnetic structures
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MFM images of a square magnetic structure
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Breaking point analysis on nano fibres
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Hexacontane
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Dendronized polymer - QI™ mode
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Polystyrene-block-polybutadiene film with QI™
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Hexaphenyl nanofibers - AFM with fluorescence microscopy
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Domain visualization in lithium niobate crystal (PFM)
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Elastomeric polypropylene - 3D views
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Hexaphenyl nanofibers
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Fluorescent polymer spheres - AFM with fluorescence microscopy
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Polyelectrolyte shell - AFM with DIC
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Hollow microcapsules
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Polymer nanoparticles
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Polymer nanoparticle manipulation
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Polystyrene surface with holes
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PHB-PHV spherulites
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SBS triblock copolymer
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Langmuir blodgett film
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Patterned PDMS polymer
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Lithography on polymer
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Polymer film
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ITO on glass
NanoWizard® BioScience AFM
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Living A549 cells - Correlative AFM and STED
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Living Vero cells
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DNA Origami at 150 lines/sec
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VIDEO - Real-time rapture of microtubules - Correlative AFM and STED measurements
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VIDEO - Real-time bending of microtubules - Correlative AFM and STED measurements
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VIDEO - Stimulation of living fibroblast cells - Correlative AFM and STED measurements
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Nanoruler - AFM and STED
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Living A549 cells - Simultaneous AFM and STED
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Astrocytes
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Imaging of bacteria S-layer with QI™
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Simultaneous AFM and STED of Living fibroblasts - Actin Filament Imaging
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Simultaneous AFM and STED of Living fibroblasts
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Cell/particle interaction - AFM with confocal microscopy
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High-resolution imaging on sperm
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Living CHO cell
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Rad51 proteins bound to DNA - AFM with fluorescence microscopy
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Fibronectin unfolding
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DNA at -25 °C
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CHO cell - AFM with phase contrast
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QI™ DNA - Major and minor grooves
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Recognition microscopy on biotin bead
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Recognition on living keratinocyte cells
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DNA origami - faceman
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Twisted insulin fibrils
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Living CHO cells - AFM with fluorescence microscopy
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Tendon tissue
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Herpes Simplex Viruses
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Bacteriorhodopsin membrane - QI™ mode
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Cell division E-coli bacteria
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Human dental enamel
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VIDEO - Live CHO cell dynamics
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Tomato Bushy Stunt Virus
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Plasmid DNA imaged in HyperDrive™ mode in buffer
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KPG7 cell dynamics
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Living Candida albicans - AFM with phase contrast
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HeLa cell in buffer - AFM with STORM
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Melting of lipid domains in buffer
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Collagen in liquid, 70Hz line rate
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Lambda phage DNA in liquid
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Bacteriorhodopsin in buffer
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Living fibroblast cell - AFM with phase contrast
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Desulfobulbus bacterial cells
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Collagen fibres
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Pea starch granules
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Herpes Simplex Virus
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Living Cyanobacterium
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Living Escherichia coli bacteria
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Living dorsal root ganglion cells - AFM with DIC
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Twisted amyloid fibrils
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Collagen – AFM with phase contrast
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Glucagon fibre
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Fibrillin microfibrils
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Malaria infected red blood cells
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L929 cell filipodia
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Single waste water bacterium
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OmpF protein crystal
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Lipid bilayer - AFM with confocal microscopy
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MDCK cells - AFM with confocal microscopy
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Moth's eye
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Human lymphocyte chromosomes
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Unfixed collagen in buffer
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Ptk2 cells - AFM with fluorescence microscopy
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Living fibroblast cells – AFM with phase contrast and fluorescence
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Living fibroblast cell
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Lipid vesicles
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Moth wing scale
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Collagen manipulation
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Gold clusters in water
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REF52 cells – AFM with fluorescence
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High-resoution image of HPI layer
NanoWizard® NanoOptics A AFM
NanoWizard® ULTRA Speed A AFM
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Correlative STED and AFM images of nanorulers
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Correlative STED and AFM images of isolated sacculi of Bacillus subtilis
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VIDEO - Living KPG7 fibroblast
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VIDEO - High-speed imaging of DNA at 10 frames/sec
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VIDEO - Melting and crystallization of a PLC thin film
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VIDEO - Triangular DNA origami
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VIDEO - Soft DNA Origami in buffer
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DNA Origami
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VIDEO - PHB/V spherulite crystallization
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Living cell dynamics
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Celgard® fast scanning
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True atomic resolution of mica
NanoWizard® Sense AFM
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Kelvin Probe Microscopy (KPM) on reference sample
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Force mapping on elastomer
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Contact Resonance frequency image of glas
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DNA imaged with PeakForce Tapping mode
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Piezoresponse Force Microscopy of a ferroelectric copolymer
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Conductive AFM of a graphite-clay blend
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E. Coli bacteria in buffer
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Zeolite crystal
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Diblock copolymer
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Dendronized polymer molecule
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Dendrimer molecules
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HeLa cells in buffer
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Living CHO cell
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Xanthan molecules on mica
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SAOS cells - AFM with confocal microscopy
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Anodic aluminum
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Structured PMMA surface
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Fe-Pt nanoparticles in lipid bilayer
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PPV viruses
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DNA molecule on mica
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Polystyrene surface with a failure crack
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Phase-separated lipid bilayer
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Quantum dots manipulation
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SAOS chondrocyte cells – AFM with phase contrast
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Osteoblast cells with neuron
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Polymer beads
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Silicon calibration grid
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PHB-PHV copolymer
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Lambda-phage DNA in buffer
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H. pylori bacterium
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Erythrocyte with influenza viruses
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Ceramic material for cell growth
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Manipulation of a chromosome
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Microtubules – AFM with fluorescence
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Living neuron cell on chip
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Erythrocytes
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Human hair
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DNA-nucleosome complexes
BioMAT™ Workstation
NanoRacer®
Automated Force Spectroscopy
ForceRobot®
Optical Tweezers
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Yeast cell manipulation
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Red blood cell transportation
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Red blood cell and bead manipulation
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Force-induced rupture of a red blood cell
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Membrane tether pulling from a macrophage cell
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Fluorescence filter change during trap manipulation
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Living macrophage cell manipulation
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Red blood cell manipulation
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Recording of a confocal z-stack
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Confocal scanning combined with optical particle manipulation
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Kinesin motility
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CV-1 cells
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DNA elasticity measurement
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DNA pulling
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Fluorescent DNA Manipulation
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JPK multiplexing
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Using the Multichannel LaminarFlowCell
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Fluorescent microtubule manipulation
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Membrane tether pulling
NanoTracker™ 2
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Yeast cell manipulation
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Red blood cell transportation
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Red blood cell and bead manipulation
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Force-induced rupture of a red blood cell
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Membrane tether pulling from a macrophage cell
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Fluorescence filter change during trap manipulation
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Living macrophage cell manipulation
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Red blood cell manipulation
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Recording of a confocal z-stack
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Confocal scanning combined with optical particle manipulation
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Kinesin motility
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CV-1 cells
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DNA elasticity measurement
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DNA pulling
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Fluorescent DNA Manipulation
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JPK multiplexing
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Using the Multichannel LaminarFlowCell
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Fluorescent microtubule manipulation
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Membrane tether pulling
Cellular Adhesion / Cytomechanics
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CHO cells elasticity map with 10 µm bead
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Adhesion of CHO cell on BSA and fibronectin coated surface
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MDCK cell- MDCK cell
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Cell elasticity measurement
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Endothelial cell - endothelial cell
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Fibroblast cell - fibronectin surface
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HeLa cell - collagen
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CHO cell - collagen binding
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CHO cell elasticity
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Melanoma cell - endothelial cell
CellHesion®
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CHO cells elasticity map with 10 µm bead
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Adhesion of CHO cell on BSA and fibronectin coated surface
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MDCK cell- MDCK cell
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Cell elasticity measurement
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Endothelial cell - endothelial cell
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Fibroblast cell - fibronectin surface
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HeLa cell - collagen
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CHO cell - collagen binding
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CHO cell elasticity
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Melanoma cell - endothelial cell
Latest Images
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Piezoresponse Force Microscopy of a ferroelectric copolymer
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Living A549 cells - Correlative AFM and STED
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Living Vero cells
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DNA Origami at 150 lines/sec
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VIDEO - Stimulation of living fibroblast cells - Correlative AFM and STED measurements
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Living CHO on gold electrode
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QI™ DNA - Major and minor grooves
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QI™-EFM on NIPAM particles
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Bacteriorhodopsin membrane - QI™ mode
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Dendronized polymer
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Hexacontane
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VIDEO - Live CHO cell dynamics
High-Speed Imaging
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VIDEO - Streptavidin binding to biotinylated DNA origami at 50 frames and 5000 lines/sec
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VIDEO - High-speed imaging of DNA origami at 35 frames/sec
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VIDEO - High-speed imaging of DNA at 50 frames/sec
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DNA Origami at 150 lines/sec
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Correlative STED and AFM images of nanorulers
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Correlative STED and AFM images of isolated sacculi of Bacillus subtilis
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VIDEO - Live CHO cell dynamics
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VIDEO - Living KPG7 fibroblast
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VIDEO - High-speed imaging of DNA at 10 frames/sec
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VIDEO - Melting and crystallization of a PLC thin film
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VIDEO - Triangular DNA origami
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VIDEO - Soft DNA Origami in buffer
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VIDEO - PHB/V spherulite crystallization
AFM / OT and Advanced Optics
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Living A549 cells - Correlative AFM and STED
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Living Vero cells
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VIDEO - Real-time rapture of microtubules - Correlative AFM and STED measurements
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VIDEO - Real-time bending of microtubules - Correlative AFM and STED measurements
-
VIDEO - Stimulation of living fibroblast cells - Correlative AFM and STED measurements
-
Nanoruler - AFM and STED
-
Living A549 cells - Simultaneous AFM and STED
-
Simultaneous AFM and FLIM measurements
-
J-aggregates
-
Paracoccus Seriniphilus bacteria
-
Living CHO on gold electrode
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Simultaneous AFM and STED of Living fibroblasts - Actin Filament Imaging
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Simultaneous AFM and STED of Living fibroblasts
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Cell/particle interaction - AFM with confocal microscopy
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Cow tooth – etched - AFM with upright microscopy
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Living CHO cell
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Rad51 proteins bound to DNA - AFM with fluorescence microscopy
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CHO cell - AFM with phase contrast
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Living CHO cells - AFM with fluorescence microscopy
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Fluorescence filter change during trap manipulation
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Recording of a confocal z-stack
-
Confocal scanning combined with optical particle manipulation
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Fluorescent microtubule manipulation
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Bacteria on pyrite surface - AFM with upright fluorescence microscopy
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Mouse cerebellum tissue - AFM with upright fluorescence microscopy
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HeLa cell in buffer - AFM with STORM
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Living fibroblast cell - AFM with phase contrast
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Living dorsal root ganglion cells - AFM with DIC
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Hexaphenyl nanofibers - AFM with fluorescence microscopy
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Collagen – AFM with phase contrast
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Lipid bilayer - AFM with confocal microscopy
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MDCK cells - AFM with confocal microscopy
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Fluorescent polymer spheres - AFM with fluorescence microscopy
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SAOS cells - AFM with confocal microscopy
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Polyelectrolyte shell - AFM with DIC
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SAOS chondrocyte cells – AFM with phase contrast
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Ptk2 cells - AFM with fluorescence microscopy
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Living fibroblast cells – AFM with phase contrast and fluorescence
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Microtubules – AFM with fluorescence
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REF52 cells – AFM with fluorescence
Superresolution Microscopy (STED, STORM, PALM)
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Living A549 cells - Correlative AFM and STED
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VIDEO - Real-time rapture of microtubules - Correlative AFM and STED measurements
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VIDEO - Real-time bending of microtubules - Correlative AFM and STED measurements
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VIDEO - Stimulation of living fibroblast cells - Correlative AFM and STED measurements
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Nanoruler - AFM and STED
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Living A549 cells - Simultaneous AFM and STED
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Simultaneous AFM and STED of Living fibroblasts - Actin Filament Imaging
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Simultaneous AFM and STED of Living fibroblasts
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HeLa cell in buffer - AFM with STORM
Confocal Microscopy, FCS, FLIM, TIRF, IRM
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Simultaneous AFM and FLIM measurements
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Cell/particle interaction - AFM with confocal microscopy
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Recording of a confocal z-stack
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Confocal scanning combined with optical particle manipulation
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Lipid bilayer - AFM with confocal microscopy
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MDCK cells - AFM with confocal microscopy
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SAOS cells - AFM with confocal microscopy
Fluorescence Microscopy
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Rad51 proteins bound to DNA - AFM with fluorescence microscopy
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Living CHO cells - AFM with fluorescence microscopy
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Fluorescence filter change during trap manipulation
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Fluorescent microtubule manipulation
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Hexaphenyl nanofibers - AFM with fluorescence microscopy
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Fluorescent polymer spheres - AFM with fluorescence microscopy
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Ptk2 cells - AFM with fluorescence microscopy
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Microtubules – AFM with fluorescence
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REF52 cells – AFM with fluorescence
Phase Contrast and DIC
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Living Vero cells
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Living CHO cell
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CHO cell - AFM with phase contrast
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Living fibroblast cell - AFM with phase contrast
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Living dorsal root ganglion cells - AFM with DIC
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Collagen – AFM with phase contrast
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Polyelectrolyte shell - AFM with DIC
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SAOS chondrocyte cells – AFM with phase contrast
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Living fibroblast cells – AFM with phase contrast and fluorescence
Upright Microscopy
Life Sciences
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DNA imaged with PeakForce Tapping mode
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Living A549 cells - Correlative AFM and STED
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Living Vero cells
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DNA Origami at 150 lines/sec
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Astrocytes
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Imaging of bacteria S-layer with QI™
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High-resolution imaging on sperm
-
DNA on octadecylamine
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DNA at -25 °C
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QI™ DNA - Major and minor grooves
-
Recognition on living keratinocyte cells
-
DNA origami - faceman
-
Twisted insulin fibrils
-
Tendon tissue
-
Herpes Simplex Viruses
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Bacteriorhodopsin membrane - QI™ mode
-
Cell division E-coli bacteria
-
Human dental enamel
-
Tomato Bushy Stunt Virus
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Kinesin motility
-
Plasmid DNA imaged in HyperDrive™ mode in buffer
-
KPG7 cell dynamics
-
Living Candida albicans - AFM with phase contrast
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Living KPG7 cell at 37°C - AFM and phase contrast
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Melting of lipid domains in buffer
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Collagen in liquid, 70Hz line rate
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Lambda phage DNA in liquid
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Bacteriorhodopsin in buffer
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Living fibroblast cell - AFM with phase contrast
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Desulfobulbus bacterial cells
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Collagen fibres
-
Pea starch granules
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Herpes Simplex Virus
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Living Cyanobacterium
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Living Escherichia coli bacteria
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Twisted amyloid fibrils
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E. Coli bacteria in buffer
-
Glucagon fibre
-
Fibrillin microfibrils
-
Malaria infected red blood cells
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HeLa cells in buffer
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L929 cell filipodia
-
Living CHO cell
-
Single waste water bacterium
-
Xanthan molecules on mica
-
OmpF protein crystal
-
Moth's eye
-
Fe-Pt nanoparticles in lipid bilayer
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PPV viruses
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Human lymphocyte chromosomes